이남규 | 바이오융합대학 의생명과학부
교수소개
https://cmbsince2023.imweb.me/
교육철학
따듯한 마음을 가진 과학자 양성
학력
- [2016] 박사 포항공과대학교 / 생명과학과
주요경력
- University of Massachusetts Medical School (2016-09-01)
주요연구분야
암대사, 셀레늄 생물학, 중간대사물의 비정형적 역할 연구, 선천성 대사질환, ferroptosis, 암-신경세포 상호작용
컨설팅 가능 분야
암대사, 대사 관련 실험 기술 (Seahorse assay, Metabolite profiling 등), 종양학 동물 실험 모델 (Xenographt, PDX), Protein-protein interaction, 셀레늄 대사, 간암, 유방암, 뇌암, 혈액암 발병 기전 연구 등
CRISPR pooled screen, Metabolomics, Development of metabolite detection method, PDX mouse model (liver, breast, and leukemia), PDO culture, Measurement of mitochondria energetic activity using Seahorse XF analyzer and FACS, Cell biology-related in vivo and various in vitro assays (xenograft assay, genetic mouse model, quantification of RNA, DNA and proteins), CRISPR-Cas9 mediated gene editing, Analysis of cancer-related datasets (DEPMAP, TCGA), Ferroptosis related assays, xCT activity measurement related assays (Ellman’s test, selenium uptake assay, selenide detection-conceived by our group), Identification of binding proteins with affinity purification
연구업적
- 일반논문[20250201] SYNCRIP promotes cell cycle progression and lung tumorigenesis by modulating AURKB translation
- 일반논문[20250201] Adapt or Perish: Efficient Selenocysteine Insertion Is Critical for Metastasizing Cancer Cells
- 일반논문[20240801] Extracellular flux assay (Seahorse assay): Diverse applications in metabolic research across biological disciplines
- 일반논문[20240213] Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
- 일반논문[20240129] From odor to oncology: non-canonical odorant receptors in cancer
- 일반논문[20231025] Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells
