한규동 사진

한규동 | 의과대학 의예과

  • 직급:
    교수

교수소개

단국대학교 미생물학과를 2000년에 졸업한 후, 동대학원에서 손승렬 교수님의 지도하에 Phenanthrene을 분해하는 Sphingomonas의 특성과 계통 유전학적 연구로 석사학위를 하였고, 미국 바톤루지에 있는 Louisiana State University 생물학과에서 Dr. Batzer의 지도하에 인간과 침팬지 종에서 레트로트렌스포존에 의해 유발되는 유전체 유동성에 관한 연구로 3년만에 박사학위를 취득하였습니다. 박사학위 과정 동안 루이지에나 주립대에서 기초생물학실험, 생화학 실험, 그리고 분자 유전학을 가르쳤으며, 2006년 생물학과에서 매년 단 한 명에게만 주어지는 William H. Gates (Teaching Excellence) award를 받았습니다. 동실험실에서 박사 후 연구과정으로 3년 재직하였고, 이 과정동안 두편의 science 논문을 포함해 총 11편의 SCI논문을 발표하였습니다. 이러한 연구성과 때문에 2007년 과학기술부로부터 "미래를 여는 우수 과학자 10인"에 선정되었습니다. 2009년 7월 두번째 박사 후 연구과정으로 텍사스 어스틴 대학에 분자 유전학/미생물학과 Dr. Sawyer lab에 합류하였고, 이곳에선 레트로바이러스들에 의해 감염된 세포의 세포질에서 레트로바이러스의 감염을 저해하는 유전자와 단백질을 연구하였습니다. 이후 2010년 9월부터 단국대학교 생명과학부 미생물학과 교수로 재직 중입니다.

2012.01 ~ 현재: DTiNa (DKU-Theragen institute for NGS analysis) 연구소장
2019.06 ~ 현재: 바이오의료공학 핵심연구지원센터 센터장
2019.09 ~ 2024.02: 단국대학교 천안캠퍼스 공동기기센터 센터장
2021.07 ~ 2024.02: 미래융합연구원 원장
2021.10 ~ 현재: (주)휴앤바이옴 최고 기술 책임자(CTO)
2023.02 ~ 현재: Genes & Genomics 편집장(Editor-in-Chief)
2024.04 ~ 현재: DCIC (DKU-COSMAX Innobeauty Center) 센터장
2024.09 ~ 2025.08: J1-Research Scholar (Faculty) at University of Florida, USA

[주요 수상]
2006. William H. Gates Award for Teaching Excellence, 루이지애나 주립대학교
2007. 미래를 여는 우수과학자 10인, 부총리 겸 과학기술부장관상
2021. 산학협력 유공표창, 부총리 겸 교육부장관상
2022. 범은학술상(연구업적부문), 단국대학교
2024. 한국유전학회 생명과학자상

학력

  • [2000] 학사 단국대학교(천안캠퍼스) / 미생물학
  • [2002] 석사 단국대학교(천안캠퍼스) / 미생물학 / 미생물학
  • [2006] 박사 Louisiana State Univ. Agricultural and Mechanical College / 생물학과 / 생물정보학

주요경력

  • Louisiana State University (2006-08-01)
  • University of Texas Austin (2009-07-01)

주요연구분야

인간 및 영장류 유전체 불안정성
레트로트렌스포존을 이용한 계통 분석학
비교 유전체학과 군집 유전학
암 유전체학
분자진단 키트 개발
Next-Generation Sequencing (Whole genome sequencing, Exome sequencing, transcriptome, and Metagenomics)
Skin Microbiome 및 디지털 플랫폼

컨설팅 가능 분야

유전자 마커 개발
레트로트렌스포존에 관련된 질병 탐지
생물정보학 프로그램 개발

연구업적

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  • 일반논문[20240401] Research Note: Possible influence of thermal selection on patterns of HSP70 and HSP90 gene polymorphisms in Thai indigenous and local chicken breeds and red junglefowls
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  • 일반논문[20220101] A qRT-PCR Method Capable of Quantifying Specific Microorganisms Compared to NGS-Based Metagenome Profiling Data
  • 일반논문[20211201] Comparative analysis of human facial skin microbiome between topical sites compared to entire face
  • 일반논문[20211101] Diagnostic evaluation of qRT-PCR-based kit and dPCR-based kit for COVID-19
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  • 일반논문[20210901] Investigation of single nucleotide polymorphism in TSH-β and CaSR associated with body weight in Korean native chickens (Gray Brown)
  • 일반논문[20210901] High-accuracy quantitative principle of a new compact digital PCR equipment: Lab on an array
  • 일반논문[20210810] Nuku, a family of primate retrocopies derived from KU70
  • 일반논문[20210801] Clinical usefulness of anti-muscarinic type 3 receptor autoantibodies in patients with primary Sjogren's syndrome
  • 일반논문[20210801] Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBP alpha, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo
  • 일반논문[20210601] Comparative Analysis for Genetic Characterization in Korean Native Jeju Horse
  • 일반논문[20210401] A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome
  • 일반논문[20210401] Influence of yeast hydrolysate supplement on growth performance, nutrient digestibility, microflora, gas emission, blood profile, and meat quality in broilers
  • 일반논문[20210401] N,N-Dimethyl-4,4 '-azodianiline functionalized magnetic nanoparticles for enhanced sensitivity of nucleic acid amplification tests
  • 일반논문[20210401] Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells
  • 일반논문[20210302] Label-Free Electrochemical Biosensor Based on Au@MoS2-PANI for Escherichia coli Detection
  • 일반논문[20210201] L1 retrotransposons exploit RNA m(6)A modification as an evolutionary driving force
  • 일반논문[20210201] Role of Transposable Elements in Gene Regulation in the Human Genome
  • 일반논문[20210105] Modulation of Human Mesenchymal Stem Cells by Electrical Stimulation Using an Enzymatic Biofuel Cell
  • 일반논문[20210101] The effect of taxonomic classification by full-length 16S rRNA sequencing with a synthetic long-read technology (vol 11, 1727, 2021)
  • 일반논문[20201201] Molecular subtypes of triple-negative breast cancer: understanding of subtype categories and clinical implication
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  • 일반논문[20201101] AbaR is a LuxR type regulator essential for motility and the formation of biofilm and pellicle in Acinetobacter baumannii
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  • 일반논문[20201001] A comprehensive analysis of chimpanzee (Pan Troglodytes)-specific AluYb8 element
  • 일반논문[20200901] A single-tube sample preparation method based on a dual-electrostatic interaction strategy for molecular diagnosis of gram-negative bacteria
  • 일반논문[20200801] Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBPα, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo
  • 일반논문[20200801] Performance comparison of fecal preservative and stock solutions for gut microbiome storage at room temperature
  • 일반논문[20200701] Differential expressions of L1-chimeric transcripts in normal and matchedcancer tissues
  • 일반논문[20200601] Enhanced Inner-Ear Organoid Formation from Mouse Embryonic Stem Cells by Photobiomodulation
  • 일반논문[20200401] Application of NanoString Technologies in angioimmunoblastic T Cell Lymphoma
  • 일반논문[20200301] Quantitative evaluation of the molecular marker using droplet digital PCR
  • 일반논문[20200201] Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations
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  • 일반논문[20190701] A comprehensive analysis of the Baboon-specific full-length LINE-1 retrotransposons
  • 일반논문[20190701] Comparison of library construction kits for mRNA sequencing in the Illumina platform
  • 일반논문[20190420] A comprehensive analysis of chimpanzee (Pan troglodytes)-specific LINE-1 retrotransposons
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  • 일반논문[20190125] Novel Discovery of LINE-1 in a Korean Individual by a Target Enrichment Method
  • 일반논문[20181228] MicroRNAs in Autoimmune Sjögren’s Syndrome
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  • 일반논문[20180601] Virulence properties of uropathogenic Escherichia coli isolated from children with urinary tract infection in Korea
  • 일반논문[20180601] Complete genome sequence of uropathogenic Escherichia coli isolate UPEC 26-1
  • 일반논문[20180401] KoVariome: Korean National Standard Reference Variome database of whole genomes with comprehensive SNV, indel, CNV, and SV analyses
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  • 일반논문[20171201] Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis
  • 일반논문[20171001] Structural variations generated by simian foamy virus-like (SFV) in Crocodylus siamensis
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  • 일반논문[20161201] Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism
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  • 일반논문[20160201] Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle
  • 일반논문[20160201] Whole Genome Re-sequencing of Three Domesticated Chicken Breeds
  • 일반논문[20160101] Analysis of L1-chimeric transcripts derived from bidirectional promoter of human-specific L1
  • 일반논문[20151201] Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution
  • 일반논문[20151201] identification of transposable element-mediated deletions in 27 korean individuals based on whole genome sequencing data
  • 일반논문[20151101] Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice
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