김형건 사진

김형건 | 의과대학 의예과 (의학관)

  • 직급:
    교수

교수소개

고려대학교 의과대학을 졸업하고 동 대학원에서 박사학위를 취득하였으며 중추신경계약리학과 임상약리학을 전공하였다. Georgetown University Medical Center의 Biochemistry/Molecular Biology와 미국 NIH의 NIMH (National Institute Mental Health) 임상약리학과에서 박사후 과정을 마치고 1997년부터 단국대학교에서 근무하고 있으며 2004년부터 2006년까지 Duke University Medical Center의 정신과에서 Senior Research Associate로 연수하였다. 의학과 1학년 "약리학 및 실습"과 의학과 3학년 "임상약리학" 과목을 담당하고 있다. 현재 의생명과학기술연구센터장과 단국대학교 병원의 생물학적동등성시험센터장을 겸직하고 있으며, 퇴행성신경손상, 골다공증 관련 신약후보 물질 발굴 및 분석, 미세투석, 신경전달물질 분석, 생체내 약동학실험, 임상시험등을 수행하고 있다.

학력

  • [1986] 학사 고려대학교 / 의학과
  • [1988] 석사 고려대학교 / 의학과 / 퇴행성뇌질환
  • [1997] 박사 고려대학교 / 약리학 / 퇴행성뇌질환

주요연구분야

미세투석(뇌, 말초조직)
뼈 관련질환 (골다공증, 관절염) 치료약물 개발
생물학적동등성시험
생체내 약동학시험
신경전달물질 분석
유전자 변형 쥐 (tansgenic/knockout mouse)의 신경계 변동 및 행동변화 평가
임상시험
퇴행성 신경질환 및 정신질환 동물모델 확립 및 치료약물 개발

컨설팅 가능 분야

(1) 신경전달물질들의 미세분석 (2) 뇌 및 기타 조직에서의 Microdialysis (3)
Rat 및 mouse에서 동,정맥 catheterization에 의한 약물력학
(pharmacokinetics) 검사 (4) 뇌 특정부위에 대한 약물이나 독성물질의 선택
적 주입에 의한 모델동물 생성

연구업적

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  • 일반논문[19990430] Effects of Dexamethasone and DHEA on the Response of Rat Cerebal Cortical astrocytes to Lipopolysaccharide and antimycin A
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