곽상준 사진

곽상준 | 의과대학 의예과

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    명예교수

교수소개

서울대학교 의과대학에서 의학과를 졸업하고(1983), 동 대학원에서 석사 및 박
사학위을 취득하였다. 대학원 과정의 주된 연구과제는 화학물질로 야기되는
전암성 병변의 발생기전과 GSH관련 해독효소들이다. 미국(뉴욕)의
Rockefeller 대학에서 티로신인산화효소(특히 src family)에 대한 주제로 해외
연수를 하였다. 현재 주된 관심사는 조골세포의 분화과정과 관련된 신호, 그
중 특히 전사인자 및 NR관련(특히 GR) 기전의 분석이다.

학력

  • [1978] 학사 서울대학교 / 의학
  • [1983] 학사 서울대학교 / 의학 / 의학
  • [1989] 석사 서울대학교 / 의학
  • [1992] 박사 서울대학교 / 의학 / 생화학

주요연구분야

Mammalian expression vector system
differentiation of MSC

컨설팅 가능 분야

중배엽미분화세포의 분화 및 조절
전사관련 연구(chromatin remodeling)
포유동물 단백질 발현 vector의 개발

연구업적

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  • 일반논문[20080115] Mechanisms of mammalian polo-like kinase 1 (Plk1) localization: Self- versus non-self-priming
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  • 일반논문[20050630] COX-2 inhibits anoikis by activation of the PI-3K/Akt pathway in human bladder cancer cells
  • 일반논문[20050531] Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells
  • 일반논문[20031204] Coordinate expression of the alpha and beta subunits of heterotrimeric G proteins involves regulation of protein degradation in CHO cells
  • 일반논문[20031130] A549 폐암세포주의 방사선-유도성 세포사에서 NF-kB 활성화 및 cIAP 발현
  • 일반논문[20031031] NF-kB is involved in the TNF-a induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARgamma expression
  • 일반논문[20021130] Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in SNU-16 human stomach cancer cell
  • 일반논문[20020531] Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells.
  • 일반논문[20010130] 폐상피세포에서 Triptolide에 의한 NFkB의존성 IL-8 유전자 전사활성 억제기전
  • 일반논문[20000831] Production and Characterization of Immortalized Rat Hepatocytes Secreting Hepatocyte Growth Factor/Scatter Factor
  • 일반논문[20000531] 폐상피세포에서 Dexamethasone에 의한 NF-kB Transactivation 억제기전에 관한 연구
  • 일반논문[19990701] Expression of SET is modulated as a function of cell proliferation
  • 일반논문[19990430] Characterrization of the alteration of cell cycle parameters associated with v-Src overexpression
  • 일반논문[19990220] Aging Process Is Accompanied by Increase of Transglutaminase C
  • 일반논문[19980425] MOLECULAR SCREENIN AND ANALYSIS OF LIGAND PROTEINS ASSOCIATING WITH UNIQUE-SH3 DOMAIN OF c-YES
  • 일반논문[19970704] Characterization of the WW domain of human Yes-associated protein and its polyproline-containing lig
  • 학술발표[20051116] 줄기세포에서 조골세포로의 분화
  • 학술발표[20051026] MGC33607 is centrosomal locating protein and knock-down by RNAi induces some mitotic defect.
  • 학술발표[20031216] Cell senescence of human MSC; Profile of differentiation potential during ageing process in MSC
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